Module 01 · Gastroenterology

The GI boards, the way clinicians think.

The Board Pearls gastroenterology curriculum: 36 chapters across 9 clinical modules, organized by the decision workflow you actually use at the bedside. Clinical vignettes, short podcast episodes, guideline-anchored study guides, and a cross-chapter question bank. Chapter 1 is free. Subscribe to unlock the rest.

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36 chapters live1657 vignette questions47 podcast episodes

The curriculum

36 chapters · 9 clinical modules · 1657 questions

Module 01

Esophagus

5 ch · 165 Q

Esophageal Symptoms and Diagnostic Workup

Sort esophageal symptoms before an… · globus and rumination as the brain… · odynophagia as mucosal injury (HSV… · CMV at the base)

Esophageal Motility

Read a high-resolution manometry t… · II · and III from distal esophageal spasm · jackhammer

GERD and Refractory Reflux

The Lyon Consensus framework for p… · when it doesn't · and what to do with refractory sym… · vonoprazan and other PCABs

Barrett Esophagus and Esophageal Cancer

Prague C and M criteria · surveillance intervals by dysplasi… · RFA and EMR or ESD for dysplasia a… · and the divergent management pathw…

Eosinophilic and Infectious Esophagitis

Eosinophilic esophagitis from diag… · the PPI / topical steroid / dietar… · and dupilumab for refractory disea… · Candida

Module 02

Stomach & Duodenum

3 ch · 131 Q

Peptic Ulcer Disease and H. pylori

ACG bismuth quadruple as first-line · vonoprazan dual and triple after f… · salvage therapy after culture and… · NSAID ulcer prevention strategy

Gastritis, Gastric Cancers, and Submucosal Tumors

Autoimmune atrophic gastritis thro… · OLGA and OLGIM staging · MALT lymphoma · and Lauren intestinal versus diffu…

Upper GI Bleeding

Glasgow-Blatchford and AIMS65 risk… · restrictive transfusion thresholds · Forrest classification · endoscopic dual therapy

Module 03

Small Bowel

4 ch · 119 Q

Gastric and Small Bowel Motility

Gastroparesis in the GLP-1 era · the 4-hour gastric emptying scinti… · and what to do when symptoms don't… · chronic intestinal pseudo-obstruct…

Celiac Disease and Sprue Spectrum

TTG-IgA plus DGP serology · Marsh and Oslo classifications · gluten-free diet with mucosal heal… · dermatitis herpetiformis

Small Bowel Mucosal Disease

Non-celiac gluten sensitivity · autoimmune enteropathy · Whipple disease (PAS-positive macr… · oculomasticatory myorhythmia)

Chronic Diarrhea and Malabsorption

Sort osmotic versus secretory vers… · then route to bile-acid malabsorpt… · microscopic colitis · dumping after Billroth

Module 04

Colon

3 ch · 154 Q

IBS and Functional Bowel

Rome IV positive diagnosis · low-FODMAP Monash 3-phase · rifaximin retreatment criteria · eluxadoline

Inflammatory Bowel Disease

Both ulcerative colitis and Crohn'… · infliximab salvage decisions · biologic positioning across SEQUEN… · JAK and S1P modulator place in line

Colorectal Cancer, Polyps, and Diverticular Disease

USPSTF age-45 screening · ADR benchmarks · USMSTF post-polypectomy surveillan… · FAP/AFAP/MAP polyposis

Module 05

Pelvic Floor & Anorectal

1 ch · 40 Q

Pelvic Floor and Anorectal Disorders

Rome IV constipation · the secretagogue ladder (linaclotide · plecanatide · tenapanor)

Module 06

Liver

8 ch · 371 Q

Liver Test Interpretation and Workup

The R-ratio framework that turns a… · cholestatic · or mixed pattern · then the noninvasive fibrosis tool…

Viral Hepatitis

HBV serology phases and the enteca… · reactivation prophylaxis around ri… · HBV in pregnancy with TDF for high… · HCV pan-genotypic DAAs in 8 versus…

Drug-Induced Liver Injury and Acute Liver Failure

Hy's Law · the R-ratio for DILI pattern · acetaminophen with the NAC 21-hour… · the King's College criteria for tr…

Autoimmune and Cholestatic Liver Disease

Autoimmune hepatitis with the simp… · the cholangiocarcinoma surveillanc… · and the Lindor high-dose UDCA harm…

Steatotic Liver Disease

MASLD per the Rinella criteria · MetALD versus alcohol-associated b… · FIB-4 and FibroScan thresholds for… · resmetirom approval scope

Inherited Liver Diseases

Hereditary hemochromatosis (HFE C2… · phlebotomy targets) · Wilson disease (ATP7B · chelators plus zinc)

Portal Hypertension and Cirrhosis Complications

Baveno VII variceal prophylaxis · refractory ascites and TIPS criteria · SBP with Sort albumin · HRS-AKI on terlipressin per CONFIRM

Liver Tumors and Transplantation

Benign liver lesions and when biop… · LI-RADS for hepatocellular carcinoma · Milan and the expanded transplant… · atezolizumab plus bevacizumab as f…

Module 07

Pancreas & Biliary

4 ch · 284 Q

Acute Pancreatitis

Revised Atlanta classification · lactated Ringer's resuscitation pe… · the etiologic workflow · same-admission cholecystectomy per…

Chronic Pancreatitis, Pancreatic Cysts, and Pancreatic Neoplasms

TIGAR-O and M-ANNHEIM grading · PERT dosing for exocrine insuffici… · IPMN surveillance per Fukuoka and… · autoimmune pancreatitis types 1 an…

Biliary Tract Disease

Symptomatic cholelithiasis · the Tokyo Guidelines for cholecyst… · ASGE choledocholithiasis stratific… · gallbladder polyps and the maligna…

ERCP and EUS Procedures

ERCP cannulation strategy · post-ERCP pancreatitis prevention… · EUS FNA versus FNB tissue acquisit… · direct endoscopic necrosectomy via…

Module 08

Endoscopy & Procedures

2 ch · 141 Q

Endoscopy Practice and Sedation

Pre-procedure fasting windows · pregnancy testing rules · the ASGE periprocedural antithromb… · sedation tier selection

Colonoscopy Practice and Quality

USPSTF age-45 screening · ADR and withdrawal-time benchmarks · the bowel-prep choice cascade (spl… · low-volume

Module 09

Cross-Cutting Topics

6 ch · 252 Q

GI Emergencies

Massive upper GI bleeding resuscit… · ischemic bowel triage · toxic megacolon decisions · acute liver failure as a code

GI Nutrition

Refeeding syndrome thresholds and… · micronutrient deficiency patterns… · enteral feeding access selection (NG · NJ

GI Infections

Clostridioides difficile diagnosis… · fidaxomicin versus vancomycin sele… · FMT and bezlotoxumab for recurrent… · travelers' diarrhea

GI in the Immunocompromised Host

Solid-organ transplant GI (CMV · PTLD · post-transplant GVHD) · HIV GI manifestations stratified b…

GI in Pregnancy

Pregnancy physiology and the norma… · the ICP / HELLP / AFLP triage in t… · hyperemesis gravidarum · GERD and PUD management with safe…

Hereditary GI Cancer Syndromes

The diagnostic framework that sepa… · Lynch syndrome surveillance · FAP/AFAP/MAP polyposis · Peutz-Jeghers and juvenile polyposis